Best Clinical Trial Management System Software

Best clinical trial management system software includes Halemind, MasterControl, BioClinica Express, OpenClinica, and Ennov CTMS. Clinical trials software is a centralized, web-based enterprise resource to support clinical research studies conducted within or across the three institutions.

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Reviewed and Edited by Supriya Bajaj
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Most Popular Clinical Trial Management System

This listing showcases software based on user recommendations and popularity. It also highlights products from our valued client partnerships.

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List of 20 Best Clinical Trial Management System

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Emergents | 2025

Product Description

MasterControl is quality clinical trial management software that maintains uniformity in your operations and accelerates them at every level. It maintains the entire life cycle of the product under trial and helps you yield results faster. Read More About MasterControl

MasterControl Is Tailored For

StartUps

SMBs

Mid-Market

Enterprises

Features

  • Multi Department Collaboration
  • Quality Event Management
  • Nonconformance Tracking
  • Regulatory Compliance
  • Risk Management
  • Integration With Other Systems
  • Capa Integration
  • Document Control
  • View all Features

Business

$ 1000

Per Month

Get Pricing

MasterControl Features and Usability-Based User Satisfaction Score

Freshness Score 9.5

Freshness Score

Out of 10

Social Score 5.0

Social Score

Out of 10

Emergents | 2025

Product Description

BioClinica Express helps medical research companies develop new clinical methods and corrective therapies. Clinical data management software offers drug safety programs, patient safety, and scientific medical expertise at affordable costs. Read More About BioClinica Express

BioClinica Express Is Tailored For

StartUps

SMBs

Mid-Market

Enterprises

Features

  • Mobile Access
  • Study Planning
  • Adverse Event Reporting
  • Protocol Deviation Tracking
  • Audit Trails
  • Risk Based Monitoring
  • Data Management
  • Reporting And Analytics
  • View all Features

BioClinica Express Features and Usability-Based User Satisfaction Score

Freshness Score 6.5

Freshness Score

Out of 10

Social Score 5.0

Social Score

Out of 10

Emergents | 2025

Product Description

OpenClinica is one of the most comprehensive CTMS software available in the market that reduces your data management efforts by creating a centralized data storage system on the cloud. The clinical trial data management software enables you to do eCRF edit checks. Read More About OpenClinica

OpenClinica Is Tailored For

StartUps

SMBs

Mid-Market

Enterprises

Features

  • Data Import/export
  • Reporting And Analytics
  • Monitoring And Oversight
  • User Training And Support
  • Integration With Other Systems
  • Ecrf (electronic Case Report Forms)
  • Randomization
  • Site Management
  • View all Features

OpenClinica Features and Usability-Based User Satisfaction Score

Freshness Score 8.0

Freshness Score

Out of 10

Social Score 5.0

Social Score

Out of 10

Emergents | 2025

Product Description

"Your clinical trial operations are time-bound, leveraged, and reliable only if you start using flexible clinical trial management software, RealTime-CTMS. With electronic data collection ability and CTMS, eDOCs, and PAY integrations, it reduces your workload." Read More About RealTime-CTMS

RealTime-CTMS Is Tailored For

StartUps

SMBs

Mid-Market

Enterprises

Features

  • Mobile Access
  • Regulatory Compliance
  • Study Management
  • Electronic Data Capture (edc)
  • Site Management
  • Monitoring
  • Audit Trails
  • Customizable Dashboards
  • View all Features

RealTime-CTMS Features and Usability-Based User Satisfaction Score

Freshness Score 8.0

Freshness Score

Out of 10

Social Score 5.0

Social Score

Out of 10

Free high-end operations for academia/non-profit

Product Description

Clinical Research IO is feature-rich clinical data management software that can save up to 32% of your operational time by automating various clinical trial steps. You can eliminate manual data entry completely by using this CTMS software. Read More About Clinical Research IO

Clinical Research IO Is Tailored For

StartUps

SMBs

Mid-Market

Enterprises

Features

  • Visit Tracking
  • Remote Monitoring
  • Audit Trails
  • Integration With Edc
  • Customizable Forms
  • Monitoring
  • Protocol Deviation Tracking
  • Site Payments
  • View all Features

Contenders | 2025

Product Description

IBM Clinical Development can easily create a password-protected single sign-in interface for your organization and protect your clinical data. The clinical data management system can easily gather, organize, and analyze your data with a single click. Read More About IBM Clinical Development

IBM Clinical Development Is Tailored For

StartUps

SMBs

Mid-Market

Enterprises

Features

  • Audit Trail
  • Electronic Patient Reported Outcomes (epro)
  • Monitoring
  • Customizable Workflows
  • Mobile Access
  • Collaboration Tools
  • Role Based Access Control
  • Training And Support
  • View all Features
5.0
out of 5 (1 Review)
Features
5.0
Ease of Use
5.0
Value for Money
5.0
Customer Support
5.0
Aditya Sethi
Software Engineer

IBM Clinical Development is a good tool that offers great flexibility with its modular approach. In terms of setup, it requires IT effort. It allows entry for adverse events, medication, and drug dosage, and it offers document management.

Read Review

IBM Clinical Development Features and Usability-Based User Satisfaction Score

Rating Score 10.0

Rating Score

Out of 10

Review Score 1.0

Review Score

Out of 10

Freshness Score 9.5

Freshness Score

Out of 10

Social Score 9.0

Social Score

Out of 10

Visitor Score 4.0

Visitor Score

Out of 10

Emergents | 2025

Product Description

Designed to eliminate operational errors and delays, SimpleCTMS is a low-cost clinical data management system that can easily fit into any ecosystem. The CTMS software supports 21 Part 11 and multi-study for easy operations. Read More About SimpleTrials

SimpleTrials Is Tailored For

StartUps

SMBs

Mid-Market

Enterprises

Features

  • Subject Management
  • Reporting
  • Econsent
  • Payments
  • Role Based Access Control
  • Invoicing
  • Site Management
  • Financial Management
  • View all Features

Standard

$ 99

Per Month

Get Pricing

Premium

$ 399

Per Month

Get Pricing

Premium Plus

$ 799

Per Month

Get Pricing

SimpleTrials Features and Usability-Based User Satisfaction Score

Freshness Score 8.5

Freshness Score

Out of 10

Social Score 5.0

Social Score

Out of 10

Category Champions | 2025

Product Description

This information is provided by vendor.

Halemind is an ingenious, leading-edge, and connected Electronic Health Record and Hospital Management System that provides insightful, actionable, and focused data to automate your day-to-day operations. Read More About Halemind

Halemind Is Tailored For

StartUps

SMBs

Mid-Market

Enterprises

Features

  • Reporting And Analytics
  • Patient Registration
  • Role Based Access Control
  • Inventory Management
  • Billing And Invoicing
  • Patient Portal
  • Queue Management
  • Multi Location Support
  • View all Features

Starter

$ 104

Per Year

Get Offer

Standard

$ 278

Per Year

Get Offer

Premium

$ 555

Per Year

Get Offer
5.0
out of 5 (5 Reviews)
Features
5.0
Ease of Use
5.0
Value for Money
5.0
Customer Support
5.0
Puneeth
General Physician

Prescription templates and bill templates help me a lot. Onboarding and account setup were done in no time. I liked the service and quick response. Thank you, Halemind.

Read all 5 Reviews

Halemind Features and Usability-Based User Satisfaction Score

Rating Score 10.0

Rating Score

Out of 10

Review Score 1.0

Review Score

Out of 10

Freshness Score 10.0

Freshness Score

Out of 10

Social Score 9.8

Social Score

Out of 10

Visitor Score 8.0

Visitor Score

Out of 10

Minimal data entry and maximum productivity

Product Description

Medidata CTMS enables an organization to create ad-hoc reports and personalized views related to clinical trials. The clinical data management system saves your team time and effort by gathering all the information on a centralized dashboard. Read More About Medidata CTMS

Medidata CTMS Is Tailored For

StartUps

SMBs

Mid-Market

Enterprises

Features

  • Study Planning
  • Audit Trail
  • Regulatory Compliance
  • Protocol Deviation Tracking
  • Visit Tracking
  • Patient Recruitment
  • Investigator Management
  • Reporting And Analytics
  • View all Features

Best Clinic Management,Simplified for clinic/chain

Product Description

This information is provided by vendor.

DocEngage Clinic Management has a unique set of features that help you run your clinic or clinic chain efficiently and smoothly. It is very simple for all staff to use. It has tons of features that make your clinic digitally health compliant. Read More About DocEngage Clinic Management

DocEngage Clinic Management Is Tailored For

StartUps

SMBs

Mid-Market

Enterprises

Features

  • Electronic Health Records (ehr)
  • Prescription Management
  • Sms And Email Notifications
  • Inventory Management
  • Billing And Invoicing
  • User Access Control
  • Reporting And Analytics
  • Patient Portal
  • View all Features
5.0
out of 5 (1 Review)
Features
4.0
Ease of Use
4.0
Value for Money
5.0
Customer Support
5.0
Aparna Singh
Implementation Manager

DocEngage Clinic Management is a self-explanatory product. Just one training session is all you need to get started. It also has an integrated Healthcare CRM that can significantly boost your clinic or hospital's growth. All the features are accessible from the main screen, provided the appropriate rights are granted. The product is economically priced, and the customer service is excellent.

Read Review

DocEngage Clinic Management Features and Usability-Based User Satisfaction Score

Rating Score 10.0

Rating Score

Out of 10

Review Score 1.0

Review Score

Out of 10

Freshness Score 9.5

Freshness Score

Out of 10

Social Score 9.0

Social Score

Out of 10

Visitor Score 8.0

Visitor Score

Out of 10

Contenders | 2025

Product Description

SmartSheet is the world's leading enterprise SaaS-based collaboration solution for organizations, making it easy to manage and automate work. It combines the ease of use of a spreadsheet with collaborative file sharing. Read More About Smartsheet

Smartsheet Is Tailored For

StartUps

SMBs

Mid-Market

Enterprises

Features

  • Forms
  • Reporting
  • Task Management
  • Alerts And Reminders
  • Automations
  • Mobile Access
  • Resource Management
  • File Sharing
  • View all Features

Free

$ 0

User/Month

Get Pricing

Pro

$ 9

User/Month

Get Pricing

Business

$ 32

User/Month

Get Pricing
4.5
out of 5 (13 Reviews)
Features
4.6
Ease of Use
4.6
Value for Money
4.5
Customer Support
4.2
Uma Maheshwar
Engineer

Smartsheet is great for the presentation of projects. It is reliable for tracking milestones and due dates. User-friendly interface.

Read all 13 Reviews

Smartsheet Features and Usability-Based User Satisfaction Score

Rating Score 9.0

Rating Score

Out of 10

Review Score 3.0

Review Score

Out of 10

Freshness Score 10.0

Freshness Score

Out of 10

Social Score 9.2

Social Score

Out of 10

Visitor Score 6.0

Visitor Score

Out of 10

Most Reviewed

Contenders | 2025

Product Description

This information is provided by vendor.

Clinic Management is evolving. Introducing a complete solution that digitizes the way we manage our clinics. No longer are we reliant on paper appointment books and physical patient files. Read More About KiviCare

KiviCare Is Tailored For

StartUps

SMBs

Mid-Market

Enterprises

Features

  • Payment Gateway Integration
  • Inventory Management
  • Billing And Invoicing
  • User Roles And Permissions
  • Telemedicine Integration
  • Lab Integration
  • Doctor Management
  • Calendar Integration
  • View all Features

KiviCare Core

$ 0

Single User/Full Lincence

Get Offer

KiviCare Pro

$ 59

Full Licence/Single User

Get Offer

KiviCare Extended

$ 299

Full Licence

Get Offer
4.7
out of 5 (3 Reviews)
Features
4.7
Ease of Use
4.7
Value for Money
4.7
Customer Support
4.7
Diana
Administrator

We have been using KiviCare for a long time, which has helped us offer a better experience to our patients. We can keep track of everything that is done within the clinic.

Read all 3 Reviews

KiviCare Features and Usability-Based User Satisfaction Score

Rating Score 9.4

Rating Score

Out of 10

Review Score 1.0

Review Score

Out of 10

Freshness Score 10.0

Freshness Score

Out of 10

Social Score 5.0

Social Score

Out of 10

Visitor Score 6.0

Visitor Score

Out of 10

Emergents | 2025

Product Description

EXPeRT eClinical is a cutting-edge platform designed to streamline clinical trial management with advanced data analytics and seamless integration. It enhances trial efficiency and ensures high-quality outcomes through innovative technology solutions. Read More About EXPeRT eClinical

EXPeRT eClinical Is Tailored For

StartUps

SMBs

Mid-Market

Enterprises

Features

  • Financial Tracking
  • Study Planning
  • Supply Management
  • Monitoring
  • Document Management
  • Integration With Other Systems
  • Adverse Event Reporting
  • Data Management
  • View all Features

EXPeRT eClinical Features and Usability-Based User Satisfaction Score

Freshness Score 7.0

Freshness Score

Out of 10

Social Score 5.0

Social Score

Out of 10

System by Winchester Business Systems

Product Description

Protocol Manager is a powerful tool designed to streamline intricate processes, enhancing user productivity. It simplifies complex tasks, allowing users to manage protocols effortlessly and efficiently, ultimately saving time and reducing errors in various operational workflows. Read More About Protocol Manager

Protocol Manager Is Tailored For

StartUps

SMBs

Mid-Market

Enterprises

Features

  • Reporting And Analytics
  • Data Integration
  • Quality Management
  • Security And Access Control
  • Site Management
  • Communication And Collaboration Tools
  • Subject Recruitment
  • Document Management
  • View all Features

System by ChemWare

Product Description

HORIZON LIMS is an advanced laboratory information management system offering seamless data integration, real-time tracking, and robust reporting tools. It enhances productivity, ensures compliance, and simplifies workflows, making it an essential tool for modern laboratories seeking efficiency and accuracy. Read More About HORIZON LIMS

HORIZON LIMS Is Tailored For

StartUps

SMBs

Mid-Market

Enterprises

Features

  • Adverse Event Reporting
  • Protocol Management
  • Subject Recruitment
  • Integration With Ehr/emr
  • Visit Scheduling
  • Electronic Data Capture (edc)
  • Monitoring
  • Investigator Management
  • View all Features

System by Clinipace

Product Description

Clinipace is revolutionizing clinical trials with its intuitive software, offering seamless integration, real-time data insights, and personalized support. Empowering researchers to focus on breakthroughs, Clinipace ensures efficient, accurate, and patient-centric trial management every step of the way. Read More About Clinipace

Clinipace Is Tailored For

StartUps

SMBs

Mid-Market

Enterprises

Features

  • Reporting
  • Audit Trail
  • Monitoring
  • Budget Management
  • Protocol Management
  • Subject Recruitment
  • Training Management
  • Investigator Management
  • View all Features

Emergents | 2025

Product Description

iMedNet EDC is revolutionizing the industry with its cutting-edge approach, offering unparalleled efficiency and accuracy in data management. This transformative software streamlines clinical trials, enhancing productivity and ensuring compliance, ultimately setting a new standard for electronic data capture solutions. Read More About iMedNet EDC

iMedNet EDC Is Tailored For

StartUps

SMBs

Mid-Market

Enterprises

Features

  • Monitoring
  • Protocol Deviation Tracking
  • Adverse Event Reporting
  • Medical Coding
  • User Management
  • Document Management
  • Data Management
  • Audit Trail
  • View all Features

iMedNet EDC Features and Usability-Based User Satisfaction Score

Freshness Score 6.5

Freshness Score

Out of 10

Social Score 5.0

Social Score

Out of 10

Emergents | 2025

Product Description

ClinTrial Works is revolutionizing the clinical trial industry with its cutting-edge software, streamlining processes and enhancing data accuracy. Its innovative approach significantly improves efficiency and reliability, transforming how clinical trials are conducted and managed. Read More About ClinTrial Works

ClinTrial Works Is Tailored For

StartUps

SMBs

Mid-Market

Enterprises

Features

  • Study Design
  • Site Management
  • Monitoring
  • Data Management
  • Electronic Data Capture (edc)
  • Document Management
  • Inventory Management
  • Scheduling
  • View all Features

Starter

$ 250

Per Month

Get Pricing

Growing

$ 350

Per Month

Get Pricing

ClinTrial Works Features and Usability-Based User Satisfaction Score

Freshness Score 9.0

Freshness Score

Out of 10

Social Score 5.0

Social Score

Out of 10

Emergents | 2025

Product Description

Bio-Optronics is a cutting-edge software solution designed to streamline clinical research operations, enhance data accuracy, and improve patient engagement, making it an essential tool for modern research sites aiming for efficiency and compliance. Read More About Bio-Optronics

Bio-Optronics Is Tailored For

StartUps

SMBs

Mid-Market

Enterprises

Features

  • Data Management
  • Patient Portal
  • Monitoring And Auditing
  • Electronic Data Capture
  • Subject Recruitment
  • Document Management
  • Financial Management
  • Integration Capabilities
  • View all Features

Bio-Optronics Features and Usability-Based User Satisfaction Score

Freshness Score 6.0

Freshness Score

Out of 10

Social Score 5.0

Social Score

Out of 10

Emergents | 2025

Product Description

StarLims is a leading Laboratory Information Management System software which is specially designed for startups and organizations. It offers end-to-end solutions with the Windows-based application and offers sample tracking and enrollment management all in one place. Read More About STARLIMS

STARLIMS Is Tailored For

StartUps

SMBs

Mid-Market

Enterprises

Features

  • Blinding
  • Subject Management
  • Study Management
  • Document Management
  • Inventory Management
  • User Access Control
  • Investigator Management
  • Audit Trail
  • View all Features

STARLIMS Features and Usability-Based User Satisfaction Score

Freshness Score 8.0

Freshness Score

Out of 10

Social Score 5.0

Social Score

Out of 10

FAQs

What is Clinical Trial Management System?

Clinical trial management system enables clinical trials to be managed in clinical research. It is a specialized, comprehensive project management application that takes the study team from startup, through enrollment and monitoring, to study closely.

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Last Updated: August 20, 2024